Carbonic Anhydrase IX (CA9) (Middle Region) Peptid
CA9
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN5672859
Kurzübersicht für Carbonic Anhydrase IX (CA9) (Middle Region) Peptid (ABIN5672859)
Target
CA9
(Carbonic Anhydrase IX (CA9))
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequenz
- KQLHTLSDTL WGPGDSRLQL NFRATQPLNG RVIEASFPAG VDSSPRAAEP
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Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti- CA9 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CA9 (Carbonic Anhydrase IX (CA9))
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Hintergrund
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Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
Alias Symbols: MN, CAIX
Protein Size: 459 -
Gen-ID
- 768
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NCBI Accession
- NM_001216, NP_001207
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UniProt
- Q16790
Target
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